We need DNA samples from horses who have been previously diagnosed with Anhidrosis, as well as horses who have had an offspring with Anhidrosis. If you would like to submit a sample, please click the button below and fill the survey. At the end of the survey, you’ll be able to download the sample submission forms or request that we mail you a sample collection kit. All studies are confidential, so be assured both you and your horse’s identity will not be released at any point should you decide to participate.
The odds of anhidrosis have been reported to be 21.67 times higher in horses with a family history of anhidrosis, highlighting the strong genetic component to this disease (Johnson, 2010).Here at Brooks Equine Genetics Lab our study will be focused on looking into some of the sweat genes of the horse and their genetic association to anhidrosis. If you own a horse that is diagnosed with anhidrosis, we would like you to contact us for involvement in this study. Enrollment in this study is strictly confidential, so rest assured you and your horse’s information are secure. Veterinarians are encouraged to pass on study information to clients who may be interested in participating.
Anhidrosis, also know as “non-sweaters” or “dry coat”, is a disease in horses that is characterized by the inability to sweat in response to appropriate stimuli (Hubert, 2002). Prevalence of the disorder favors hotter and more humid climates, although cases of anhidrosis have been reported in many different regions (Johnson, 2010). Any horse can become afflicted as it is not limited to any particular sex, breed, or age (Johnson, 2010). The severity of Anhidrosis can vary, however anhidrotic horses require careful observation and management as well as reduced workload or removal from physical activity. Anhidrotic horses forced to perform can suffer severe consequences, including multiple organ failure in response to hyperthermia and, in some instances, death (Evans, 1966).
Clinical Symptoms might include:
Evans, C. (1957). Physiological factors in the condition of “dry coat” in horses. Vet Rec, 1-9.
Evans, C. (1966). Physiological Mechanisms that Underlie Sweating in the Horse. Br Vet J, 117-173.
Hubert, J. D. (2002). Equine Anhidrosis. Vet Clin Equine , 355-369.
Johnson, E. B. (2010). An Epidemiologic Study of Anhidrosis in Horses in Florida. Journal of the Epidemiologic Study of Anhidrosis in Horses in Florida, 1091-1097.
MacKay, R. (2008). Quantitative Intradermal Terbutaline Sweat Test in Horses. Equine Vet Journal, 518-520.
A quantitative intradermal sweat test (with terbutaline) can be used for identification of freely sweating horses (MacKay, 2008). Currently there is no treatment for Anhidrosis that passes even the lowest standard for evidence-based medicine. Current, only good management can help prevent the anhidrotic horse from overheating.
Tips for keeping an Anhidrotic horse cool include:
Dr. Laura Patterson-Rosa, a PhD student in the Brooks Lab and a veterinarian, is working to find genes responsible for anhidrosis in the horse
Ongoing study at the University of Florida
Please contact the Brooks Equine Genetics Lab for more information. You can reach us by phone at (352) 273-8080 or email, firstname.lastname@example.org.